Layla Alvarez was last seen in Stafford on September 8, but has not been seen or heard from since, according to the AWARE Foundation.
The 16-year-old was described as 5'0 tall, with brown hair and brown eyes, and weighing 170 pounds, police reported.
Alvarez was last seen wearing a black hoodie, black leggings, and black converse sneakers, with her hair in a bun, the AWARE Foundation said.
She has a tattoo of a snake and a rose with the letters "TYL" on her right arm, the AWARE Foundation detailed.
Anyone with information on the teen's whereabouts should contact police at 540-658-4400.
Click here for more from the AWARE Foundation.
Click here to follow Daily Voice Alexandria and receive free news updates.