The closure was from I-81 N from Exit 5 Greencastle-Waynesboro to Exit 10: PA 914 Marion.
It was first reported just after 3:30 p.m. but the roadway reopened around 5 p.m., according to PennDOT spokesperson Fritzi Schreffler.
It is unclear how many vehicles and people were involved and if there were any injuries.
Check back here for updates.
This is one of two crashes that closed a highway in Central Pennsylvania. Click here to read about the crash on US22/322.
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