The crashed happened at around 6:35 a.m. Thursday at 460 Freedom Plains Road (Route 55) following a crash with a car, said New York State Trooper AJ Hicks.
The motorcyclist was ejected during the crash and died on the way to the hospital, he said.
This is a developing story. Check back to Daily Voice for updates.
Click here to follow Daily Voice Poughkeepsie and receive free news updates.