The 10th-seeded Syracuse defeated Middle Tennessee 75-50 on Sunday to move on to March Madness' Sweet 16 after beating seventh-seeded Dayton in the first round.
Dayton had defeated Syracuse in its previous NCAA Tournament game, in 2014.
Lydon scored 14 points, seven rebounds and six blocks in the match against Middle Tennessee.
Syracuse will play Gonzaga in the Midwest semifinals on Friday.
Stissing Mountain HS is in the Pine Plains Central School District.
Lydon's mother played basketball at Dutchess Community College.
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