"Sweetheart Coast" will sell clothing, accessories, home decor and gifts on the Boardwalk.
The store will open this summer, Giancola announced in a YouTube video.
Giancola has been coming to Ocean City since she was a child and said it is her "favorite place on earth.
"I couldn't think of a better place to open a store than here," she said.
Last week, Giancola's former co-star Jenni "JWoww" Farley announced she was opening a store at the American Dream Mall in Bergen County.
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