The camper flipped over on I-81 South at mile marker 84 in East Hanover Township around 11:30 a.m.
The interstate closed for the towing between Exit 85: PA 934 - Annville/ Fort Indiantown Gap and Exit 80: PA 743 - Grantville/Hershey.
No injuries were reported.
The crash appeared to have cleared just before 1 p.m. but there are some residual delays according to the traffic cameras on 511PA.
Click here to follow Daily Voice Myerstown and receive free news updates.