It happened around 4:40 p.m. near the Columbus Boulevard exit, state police wrote in a release. The debris crashed through the windshield of a Subaru Impreza and hit 33-year-old driver Caramia Panichelli, "causing fatal injuries," troopers said.
Investigators have not said where they believe the debris came from.
Troopers are seeking eyewitnesses to the crash, and anyone with information is urged to call PSP's Philadelphia station at 215-452-5216.
Click here to follow Daily Voice Drexel Hill-Upper Darby and receive free news updates.