Police will redirect traffic from Kinderkamack Road to New Milford Avenue in River Edge and to Main Street and River Road in New Milford.
The work will continue through 7 p.m. Thursday, Nov. 5 -- unless it's completed earlier, the state Department of Transportation said.
NJ Transit will provide buses.
"In order to provide a safer and smoother railroad crossing in River Edge, the existing crossing will be replaced with a new concrete crossing and new asphalt approaches," the DOT said in a release.
"This project is included within NJDOT’s railroad grade-crossing safety program which repairs, upgrades, or removes approximately 30 crossings each year, statewide.
"The precise timing of the work is subject to change due to weather or other factors. Motorists are encouraged to check NJDOT's traffic information website www.511nj.org for construction updates and real-time travel information.
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