It wasn't immediately clear why the girl was behind the wheel of the 2017 Toyota Corolla.
She was headed southbound on Broken Land Parkway when the car veered off the roadway and struck a tree just south of Cradlerock Way around 2:10 a.m. in Columbia, police said.
Southbound Broken Land Parkway was closed between Cradlerock Way and Snowden River Parkway for approximately four hours.
Click here to follow Daily Voice Columbia and receive free news updates.