Police responded to the crash off Exit 24 on I-93 north in Medford around 3:20 a.m. on Friday, Nov. 4, Massachusetts State Police report.
Initial investigation suggests the driver veered off the road and struck the guardrail, police said. High speed is believed to be a factor.
The man had to be pulled from his vehicle and was taken to Massachusetts General Hospital with serious life-threatening injuries, police said. The crash closed the entire highway for several hours.
The investigation is ongoing.
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