Brianna Madrid Orellana, 16, was last seen at her Central Islip home on Dec. 23, 2025, according to the New York State Missing Persons Clearinghouse.
Orellana wears glasses and has a birthmark on the right side of her lip, officials said.
Additional details, including a clothing description and possible destination, were not given.
Anyone with information is asked to call 1-800-346-3543.
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