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COVID-19: Study Reveals Who's Most At Risk For Breakthrough Infections

Pfizer COVID-19 vaccine
Pfizer COVID-19 vaccine Photo Credit: Flickr US Secretary of Defense

Researchers have identified groups of vaccinated people who may be the most at risk for suffering severe outcomes from COVID-19 breakthrough infections.

According to a report from Medical News Today, the study looked at more than 6 million people who have received one or two doses of COVID-19 vaccine in the United Kingdom. 

One of the paper's co-authors, Dr. Aziz Sheikh, said only a small number of the more than 5 million people who received two vaccine doses remained at risk for COVID-19 hospitalization and death after being vaccinated.

"We saw relatively few deaths in individuals who had received the second dose of the vaccine (4% of all covid-19 related deaths); therefore, most information about associations between predictors and mortality came from individuals who had received only one dose," the researchers wrote.

The researchers were able to identify which groups might be most at risk for hospitalization and death, and who might benefit from vaccine boosters and new treatments.

Medical News Today reported that researchers found the following groups of people are at higher risk for severe COVID-19 infections:

  • People with Down syndrome
  • People who have had a kidney transplant
  • People with sickle cell disease
  • Residents of care homes
  • People receiving chemotherapy
  • People who have had a recent bone marrow transplant or solid organ transplant
  • People with HIV or AIDS
  • People with dementia
  • People with Parkinson’s disease
  • People with several rare neurological conditions
  • People with cirrhosis

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