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Firefighters found flames blowing through the roof and out second-floors windows of the West Prospect Street home when they arrived around 9:30 p.m.
They had the main body of the blaze knocked in under a half hour and officially under control shortly before 11 p.m.
The extent of the residents' injuries weren't immediately known, although responders said they didn't appear life-threatening. Both were taken to The Valley Hospital in Ridgewood.
The fire went to three alarms for coverage.
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